Nearly 38 million people in the United States and 830 million worldwide live with diabetes mellitus (DM), and the burden of this disease in both cost and mortality continues to rise. Glucose detection is a cornerstone of DM and was initially used to confirm diagnosis before effective anti-hyperglycemic drugs were available. The discovery of hypoglycemia-inducing diabetes ... Continue Reading

Glucagon-like peptide-1 receptor agonists (GLP-1RA) are considered a cornerstone of type 2 diabetes and obesity treatment nowadays. These medications – the most commonly known is Ozempic – have a strong efficacy in controlling hyperglycemia and a significant effect on weight loss. Due to their effect on gastric motility, the most common side effects seen in patients starting ... Continue Reading

Sodium-glucose co-transporter 2 inhibitors (SGLT2 inhibitors) were initially intended for type 2 diabetes but quickly proved effective for cardiovascular diseases and delaying the progression of diabetic kidney disease. These medications inhibit the SGLT-2 protein, which is responsible for 90% of glucose reabsorption in the kidneys, promoting urinary glucose excretion and ... Continue Reading

As GLP-1 receptor agonists emerge as effective treatments for weight management, anecdotal reports from patients and clinicians alike point to a reduction in what has been colloquially termed “food noise.” What is Food Noise? The journal Nutrients defines “food noise” as constant, obsessive food ruminations that are hard to suppress and can even interfere with daily life. ... Continue Reading

Current data suggests that 45% of Americans are suffering from obesity compared to approximately 10% in 1980. The rate of increase is daunting and should give us all pause. Based on this data, I've concluded that I simply must do better, and to do better I have to do differently. For that reason I would like you to first look at obesity as a disease. To paraphrase the ... Continue Reading

  Over the past decade there’s been a massive increase in the development of diabetes medications. The new approach in prescribing type 2 diabetes medications is to consider all aspects of the patient’s health, such as their cardiovascular event risk, kidney health and other comorbidities. The following are the highlights from AACE guidelines on the ... Continue Reading

In the United States, just over 40% of adults are overweight (BMI 25-29kg/m2) or obese (BMI =>30kg/m2); that’s more than 2 out of every 5, somewhat over 100 million people. Thirty-eight million of us have diabetes (type 2 being the largest portion of this group at 94.3%), which amounts to roughly 14.7% of U.S. adults based on 2021 data. The percentage of undiagnosed ... Continue Reading

Postmenopausal osteoporosis is a major health problem hiding in plain sight. I say this because we see patients with osteoporosis and osteoporotic fractures every day in our clinics, but only a small percentage of these patients are properly evaluated and started on therapy. There are 10 million patients diagnosed with osteoporosis in this country, and 80% of them are women. ... Continue Reading